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Academic Year 2024–2025
Allergy and immunology is a medical specialty concerned with the evaluation, diagnosis, and management of disorders arising from dysfunction of the immune system. These include allergic diseases — such as allergic rhinitis, asthma, food allergy, drug hypersensitivity, and anaphylaxis — as well as primary immunodeficiency disorders, autoimmune conditions, and hereditary diseases of the immune system such as hereditary angioedema.[1]
More Specialty Info
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Allergy and immunology is a medical specialty concerned with the evaluation, diagnosis, and management of disorders arising from dysfunction of the immune system. These include allergic diseases — such as allergic rhinitis, asthma, food allergy, drug hypersensitivity, and anaphylaxis — as well as primary immunodeficiency disorders, autoimmune conditions, and hereditary diseases of the immune system such as hereditary angioedema.[1]
The specialty sits at a distinctive intersection of internal medicine and pediatrics. Allergist-immunologists care for patients across the full age spectrum, from infants with recurrent sinopulmonary infections to elderly patients with newly diagnosed immunodeficiency or treatment-resistant asthma. This breadth is one of the specialty's defining characteristics and contributes to its sustained appeal among graduates of both internal medicine and pediatrics training programmes.[2]
Clinical practice encompasses both diagnostic and therapeutic dimensions. Allergists perform and interpret skin prick testing, intradermal testing, patch testing, and pulmonary function studies. They administer and supervise allergen immunotherapy — the only disease-modifying treatment currently available for allergic rhinitis and venom hypersensitivity — and increasingly manage patients on biologic therapies targeting specific immune pathways in severe asthma, chronic urticaria, and atopic dermatitis.[3]
Approximately 50 million Americans are affected by allergic conditions annually, with asthma alone accounting for more than 1.6 million emergency department visits per year.[4] This growing burden, combined with a relatively small specialist workforce, means demand for trained allergist-immunologists substantially exceeds supply in most US markets.
The typical allergist-immunologist works in an outpatient clinic setting. The majority of patient encounters are scheduled office visits for ongoing management of chronic allergic conditions, immunotherapy administration and monitoring, and evaluation of new referrals. Hospital consultations — for anaphylaxis management, drug desensitisation, or evaluation of suspected immunodeficiency in complex inpatients — are more common in academic practice but constitute a smaller proportion of clinical time than in most other specialties.[2]
Practice patterns differ meaningfully between academic and private settings. Academic allergists maintain a balanced portfolio of clinical care, research, and teaching. Private practice allergists generally carry higher patient volumes with strong revenue from immunotherapy administration and biologic initiation and monitoring.[5]
Call burden is low relative to most medical specialties. Outpatient allergy practices rarely carry hospital call obligations, and this contributes to the specialty's reputation for sustainable work-life balance — consistently cited in physician satisfaction surveys as a primary driver of career satisfaction.[5]
MEDIAN (EMPLOYED)
$298,000 / year
Doximity 2023 [6]
TYPICAL RANGE
$220,000 – $450,000+
By setting, geography & volume
Allergy and immunology offers competitive compensation relative to its training length and lifestyle profile. Revenue drivers include patient volume, immunotherapy panel size, and biologic therapy management. Geographic variation is significant: allergists in underserved suburban and rural markets typically outperform urban academic counterparts on total compensation.[6]
Entry into allergy and immunology fellowship requires completion of a three-year ACGME-accredited residency in either internal medicine or pediatrics. The specialty does not offer PGY-1 positions and cannot be entered directly from medical school. Candidates completing a combined internal medicine/pediatrics residency (four years) are also eligible and are highly competitive.[7]
Fellowship training is two years in length and covers the full scope of adult and pediatric allergy and immunology. Core competencies include the diagnosis and management of asthma, allergic rhinitis, food and drug allergy, primary immunodeficiency, and urticaria/angioedema. Fellows gain supervised experience in skin testing, allergen immunotherapy initiation, pulmonary function interpretation, and oral food challenges. Research output — at minimum one project suitable for presentation or publication — is expected by most programmes.[7]
Applications are submitted through ERAS with a July programme start date. The specialty coordinates through the AAAAI/ACAAI fellowship match rather than the standard NRMP Match — applicants should verify programme-specific deadlines, which differ from the main residency match calendar.
Position fill rate
~93%
Programs requiring Step 1
~74%
Programs requiring COMLEX Level 1 (DOs)
~61%
Allergy and immunology fellowship is moderately competitive. In recent cycles approximately 90–95% of offered positions filled in the first round, with US graduates from internal medicine and pediatrics backgrounds making up the majority of successful applicants.[8] Research experience, letters of recommendation from allergist-immunologists, and dedicated clinical exposure to the specialty are the strongest differentiating factors. Competitive applicants typically present Step 1 scores above 230 and Step 2 CK scores above 245.
The workforce outlook for allergy and immunology is strongly positive. The AAAAI estimates a significant and growing shortage of practising allergists, particularly in rural and suburban markets where access to specialist care is limited.[4] Approximately 3,800 board-certified allergist-immunologists are currently active in the United States — a number that falls well short of population demand.
The training pipeline of approximately 150 new fellows per year is insufficient to offset retirements while meeting growing demand. Workforce analyses project the shortage will deepen through the 2030s, making this one of the more reliably undersupplied specialties for early-career physicians.[4]
Fellowship programmes are concentrated in academic medical centres in the Northeast, Midwest, and California. Programmes in the South and Mountain West regions tend to have lower application volumes and may offer stronger match prospects for candidates who signal genuine interest and fit.
Most programmes strongly favour applicants who completed a clinical rotation or research elective in an allergy/immunology division during residency. Attending the AAAAI annual meeting and presenting research at regional or national meetings meaningfully improve visibility with programme directors.
Physicians who thrive in allergy and immunology tend to share a few characteristics: intellectual curiosity about the immune system, patience for chronic disease management, and satisfaction in building long-term relationships with patients followed over years or decades. The specialty rewards clinicians who enjoy procedural work — skin testing, immunotherapy, oral challenges — without the demands of a primarily surgical career. Those seeking predominantly acute or hospital-based practice may find the outpatient focus limiting; for others, it represents an ideal balance of intellectual depth, procedural variety, and lifestyle sustainability.